It is a widely known fact that cannabinoids (also termed as cannabinoids) are one of the most versatile and useful treatments for many ailments. The medical benefits of this plant include the treatment of various chronic illnesses. However, the medical field has been stumped when it comes to differentiating the various compounds that are present in the plant. The high degree of complexity in cannabinoids and their therapeutic effects has led to two different names being used to describe them. The terms cannabidiol (CBD) and tetrahydrocannabinol (THC) are used interchangeably as they are both non-intoxicating compounds from the cannabis plant. They both have a variety of therapeutic and medical uses.
There are many misconceptions about THC. Many people want to know if they can use it for this or that. Many people don’t understand the difference between CBD and THC.
CBD and THC are two of the most well-studied and popular cannabinoids.
CBD is a non-psychoactive cannabinoid, while THC is the psychoactive cannabinoid.
Because of its actions on the endocannabinoid system and other receptors in the body, both cannabinoids have a variety of health benefits.
They are, nevertheless, more than these basic definitions.
We’ll go through the distinctions between THC and CBD in this post so you can choose the ideal product for your requirements.
CBD and THC have a lot in common.
Let’s start with the similarities between CBD and THC before moving on to the differences.
Hemp and marijuana, both members of the cannabis family, are used to produce CBD and THC. Hemp has more CBD than THC (up to 0.3 percent in the United States), while marijuana is defined as any cannabis plant with more than 0.3 percent THC.
Hemp with more than 0.3 percent THC is classified as marijuana.
Cannabigerol or CBG, the precursor of other cannabinoids, is the source of both cannabinoids. When CBG breaks down, it transforms into THC, CBD, CBC, and other cannabinoids.
THC and CBD both contain 21 carbon atoms, 30 hydrogen atoms, and two oxygen atoms in their chemical structure, thus they’re nearly identical molecularly.
The arrangement of their atoms is what distinguishes them, accounting for the variations in their effects.
Both activate the endocannabinoid system as well as other biological systems involved in maintaining homeostasis and symptom modulation. As a consequence, these chemicals have been well researched for their ability to decrease pain, inflammation, and promote a healthy stress and mood response, among other things.
THC and CBD both induce dry mouth. When they activate the cannabinoid receptors on the salivary glands, they decrease saliva production, resulting in the unpleasant cottonmouth feeling .
Because there are just a few cannabinoid receptors in the brain area that controls our heart and lungs, these cannabinoids will not produce an overdose. The effects of high-THC dosages may be unpleasant and even frightening, but they are not fatal.
Both cannabinoids have the potential to interact with other medicines and substances. They may either reduce or increase the effects, as well as affect the drug’s toxicity levels. As a result, we always suggest first speaking with the patient’s primary care physician about the use of medicinal marijuana.
CBD vs. THC: What’s the Difference?
CBD and THC have a lot of commonalities, but they also have a lot of differences.
Knowing the distinctions between them may help you avoid unpleasant side effects, which is particularly important if you’re taking marijuana for health reasons.
So, what’s the difference between CBD and THC?
1. Atomic Arrangement
As previously stated, CBD and THC have almost identical chemical formulas, however their atom arrangements vary.
When you look at the THC molecule, you’ll see that it contains three rings, each of which includes one oxygen atom that bonds to the rest of the molecule to create a closed shape.
CBD, on the other hand, has just two rings and an open form because the hydroxyl group (an oxygen atom linked to a hydrogen atom) is not coupled to carbon atom #5.
THC and CBD have quite distinct effects on the body because of this discrepancy.
2. Psychoactivity, Addiction, and Dependence
The CB1 and CB2 receptors are two cannabinoid receptors that make up the endocannabinoid system. Both receptors are present throughout the body, although CB1 is more prevalent in the neurological system (particularly the brain), while CB2 is more prevalent in the immunological and gastrointestinal systems.
CB2 is primarily engaged in immune response control.
CB1 is implicated in a wide range of physiological processes, including pain, memory, fear, learning, hunger, mood, emotions, motor and sensory control, pleasure, and reward.
Because the configuration of CBD and THC atoms differs, these cannabinoids bind to cannabinoid receptors in various ways.
THC binds easily to the CB1 receptor, which when activated causes psychoactive effects. You should know that CB1 is the receptor that causes the high from cannabis.
THC also raises the likelihood of marijuana dependency and addiction by activating CB1 receptors in the brain’s pleasure and reward regions.
CBD, on the other hand, has a difficult time binding to the CB1 receptor. This is why CBD won’t get you high or make you more prone to dependency and addiction.
3. Medical Insurance
Both cannabinoids have a lot of the same health advantages.
CBD, on the other hand, is increasingly being used to treat stress and anxiety. CBD helps individuals feel calmer and more in control of their stress, mood, and emotions, according to them.
When it comes to THC, many individuals find that it helps with hunger and sleep issues.
Why is it more beneficial to combine CBD and THC?
CBD and THC alone have their own set of benefits, but when combined, they become even more powerful.
The entourage effect is the result of cannabinoids acting together. This simply implies that the cannabinoids and terpenes work together to enhance each other’s positive effects, resulting in a greater impact than isolates.
CBD alone, for example, may have painkilling and anti-inflammatory properties, but these properties are restricted since CBD is only effective at a specific dosage.
CBD has a bell-shaped dose-response curve, according to experts. CBD becomes less effective if the dosage is greater or lower than the recommended therapeutic amount .
When CBD and THC are combined, however, their combined therapeutic benefits are more powerful and strong in reducing symptoms.
Is it possible to get high with CBD products that include THC?
It should not cause psychotropic effects as long as the CBD product is produced from hemp and has a concentration of up to 0.3 percent.
Furthermore, CBD reduces the psychoactive effects of THC.
CBD may not bind effectively to the CB1 receptor’s active site, but it may attach to another location on the receptor termed the allosteric site, according to research . CBD alters the shape and size of the receptor’s active site when it binds to the allosteric site, making it harder for THC to connect to the CB1 receptor and cause euphoric effects.
CBD also has a calming impact on the pleasure and reward regions of the brain, decreasing THC’s effects even further. CBD may assist with dependency and addiction issues because of this impact .
Some of the negative effects of CBD and THC are also different.
Fatigue, weight loss, dizziness, diarrhea, and low blood pressure are all possible side effects of CBD.
THC, on the other hand, may cause anxiety, paranoia, hallucinations, motor incoordination, red eyes, short-term memory loss, difficulty to concentrate, and an elevated heart rate, among other things.
Long-term and severe THC usage may lead to dependency, addiction, and long-term mental issues.
Both cannabinoids are usually well tolerated and safe. High dosages of CBD and THC, unlike opiates, do not cause life-threatening overdoses.
If the negative effects of THC become too much for you, you may decrease them by putting a few drops of CBD oil under your tongue.
You may also reduce the intensity of your THC high by focusing on anything else, such as watching a movie, cleaning your closet, or taking a shower.
You could also drink lots of water or eat some lemon or peppercorns to help with anxiousness caused by marijuana.
If you’re tired, go to bed and sleep it off.
The key thing is to avoid focusing on how stoned you are since this will just exacerbate your worry.
Legality is number five.
The legality of CBD and THC is a little hazy, so we’ll have to talk about the distinction between hemp and marijuana to have a better understanding.
Industrial hemp having less than 0.3 percent THC is allowed under the 2018 Farm Bill. Hemp with more than 0.3 percent THC is classified as marijuana and is thus illegal on the federal level.
This implies CBD derived from federally legal hemp is lawful, while CBD derived from marijuana is not.
Is there a difference between hemp CBD and marijuana CBD?
No. They’re both CBD and have the same chemical structure, regardless of the source. The legality of the source is what sets them apart.
THC is still prohibited on the federal level.
Because each state has its unique marijuana regulations, we recommend that you verify your local laws before utilizing any CBD or high-THC products produced from marijuana for medicinal or recreational purposes.
We also emphasize the significance of avoiding flying or traveling with marijuana products from a legal state to a non-legal one, or even from one legal state to another. If you’re found carrying such items, even if they’re for medicinal purposes, you may face serious consequences.
6. Testing for drugs
CBD will not show up in a standard drug test since CBD and its metabolites are not included in standard drug tests.
THC and its metabolites, particularly THC-COOH, are what standard drug tests are sensitive to.
Full-spectrum CBD products, which include THC, may result in a positive drug test. Even if the THC content is less than 0.3 percent, it may still show up on a drug test, particularly if you’ve been taking large quantities of full-spectrum CBD products for a long time.
Final Thoughts – Which is Better: CBD or THC?
Is THC superior than CBD, or will CBD provide you with greater benefits?
The one is not superior than the other. There is no simple answer to the question of whether THC or CBD is the superior cannabinoid.
They each have their own set of advantages and disadvantages.
Of course, if you want to get a bit high, go for high-THC marijuana products.
If you can’t handle THC, though, there are a variety of CBD products to select from. Pure CBD products are those that solely contain CBD. There’s also broad-spectrum CBD, which contains a variety of additional cannabinoids and terpenes.
Choose full-spectrum CBD products if you want to get the most out of the entourage effect. THC will enhance CBD’s medicinal benefits, making the product more powerful, but it will not make you high.
The most essential thing to keep in mind is to choose the product that best meets your requirements.
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