Delta-8-THC is the chemical that makes the psychoactive cannabinoid THC. It is most noted as a treatment for glaucoma, epilepsy, and chemotherapy-induced nausea and vomiting. Delta-8-THC is the second most prevalent cannabinoid found in hemp, and is one of the most beneficial plants in the hemp family. Delta-8-THC is an extremely versatile hemp compound, and has a wide range of potential applications.

While most users will know Delta-8-THC (D-8-T) as the active ingredient in medical marijuana, it is a substance used in a variety of recreational drugs, including synthetic pot Spice and “K2” (aka “Spice”). In the past decade, Delta-8-THC has received a lot of attention in the media, with many articles describing it as a real concern, while others go as far to call it a joke—as if the vast majority of recreational drug users knew anything about this compound.

Delta-8-tetrahydrocannabinol (THC) is the most commonly consumed cannabinoid found in cannabis. It’s primary use within the cannabis world is to create the famed psychoactive compound, commonly known as “THC” (Tetrahydrocannabinol).. Read more about does delta-8 thc get you high and let us know what you think.

Delta-8-THC Science

Delta8, also known as Δ8-THC, is not new to the scientific community. This is just one of over 150 identified cannabinoids produced by this amazing plant.

Δ8-THC and its better known brother Δ9-THC (as well as other isomers like Δ10-THC) have exactly the same chemical composition: C₂₁H₃₀O₂. The difference between Δ8-THC and Δ9-THC is the location of a double bond at the aromatic carbon ring.

Structure Δ8-THC.

In Δ9-THC it is located between carbons 9 and 10. For Δ8-THC it is between 8 and 9 carbohydrates. While such a change may seem small and insignificant, this small change in chemical bonding can alter the overall shape of the molecule so drastically that it is no longer recognized by the same receptors in the body, or possibly change the amount of the molecule that can be absorbed.

This change can also block receptors for other molecules or even change the shape of the receptors so that they can bind to other molecules. This type of interaction is a theory of what happens during the entourage effect between full-spectrum cannabinoids and isolated cannabinoids, so Δ8-THC may end up having a different effect than Δ9-THC.

Another possible difference that could be caused by this change in the arrangement of double bonds is the inherent stability of the chemical composition. Some studies show that Δ8-THC is more stable than Δ9-THC and does not oxidize to CBN as easily, but this is based on small chemical analyses of strictly isolated pure compounds performed in research laboratories.

Most Δ8-THC currently on the market are made using an acid, such as acetic acid or formic acid, which converts CBD into an intermediate, which can usually be Δ9-THC. This intermediate chemical reaction is then neutralized by an alkaline solution containing chemicals such as pentane.

Structure Δ9-THC

Sometimes the reaction requires a catalyst, such as boron trifluoride or magnesium silicate. Finally, the mixture is neutralized with compounds such as sodium bicarbonate before the Δ8-THC can be collected from the final solution.

There are other methods, but they are usually owned by third parties and competition prevents many of them from being published and studied.

However, this process uses some dangerous chemicals, and even if you end up with a 95% pure Δ8-THC isolate, the question remains as to what the other 5% of the compound is.

Does this form of Δ8-THC remain as stable in this state and with these synthetic methods as previous small-scale pure crystallization methods?

What degradation takes place and under what conditions during synthesis and storage? What traces of solvents remain? What is the purity of the chemicals used by the manufacturer?

It is issues such as these that demonstrate the need for further research, testing, transparency and verifiable data to get a clear picture of the use or consumption of these products.

Chromatogram for Δ8-THC

This lack of transparency and uncertainty not only poses problems for the protection of consumers of Δ8-THC.

Testing laboratories across the country are faced with the problem of Δ8-THC samples that are thought to be isolated or pure Δ8, but contain dramatically high levels of Δ9-THC that exceed current regulatory limits.

Existing theories on the causes of this non-compliance include factors such as stable and accurate production processes, proper sample handling and preparation, accurate testing methods, proper testing equipment, stability of Δ8-THC under current production processes and storage conditions, and the perennial problem of cannabis and the cannabis industry: unscrupulous, unethical or ill-informed companies.

Industry today

Early studies in the 1970s showed that Δ8-THC could reduce the size of tumors in mice, and by the 1980s it was discovered to be a slightly less potent bronchodilator than the better-known cannabinoid and its closely related isomer Δ9-THC. Although cannabinoid research has never been abundant in the United States, it has all but ceased since the late 1980s.

Therefore, most research is done in other countries, especially in Israel. In the 1990s, Israeli researchers found evidence that Δ8-THC reduced symptoms of nausea in children with cancer.

In the 2000s, other studies linked it to a possible increase in appetite and an effect on important neurotransmitters. Apart from these few limited studies, which were not widely published and largely involved mouse models, no one has really looked into such an unimportant cannabinoid.

All studies conducted focused on the better known Δ9-THC/THCA. Any mention of Δ8-THC has been reduced to obscure passages on internet forums like Erowid, or verbally passed on rumors in secret tribes of stoners.

Even after medical marijuana guidelines and laws were passed in California, then Colorado, Washington, Oregon and elsewhere, this obscure cannabinoid remained in the shadows.

That all changed with the passage of the 2018 Farm Bill, and with it, cannabis production exploded in the United States. This increase in cannabis cultivation across the country has led to a new wave of research into the effects of lesser-known cannabinoids: Producers, processors and consumers have begun researching cannabinoids in hopes of finding the next CBD.

As the market became flooded with all kinds of CBD products and prices began to fall due to oversupply, some people began to process the excess CBD into Δ8-THC, which is still largely unknown and sold for ten times or more the price of CBD. Because Δ8-THC is not technically listed in the Pesticide Act, but has been listed by the DEA in the past, these business owners were counting on a technical reading of the 2018 Farm Bill..

Because this Δ8-THC came from the now-legal cannabis, it was considered a way to get high without breaking federal law. But is it really legal? The DEA has a specific position on this issue, recently clarified in the publication of the Interim Final Rules on Hemp, which state that synthetic cannabinoids are also considered marijuana and are controlled substances.

This means that Δ8-THC is still a Schedule 1 controlled substance according to the DEA and U.S. law enforcement agencies and as such is in no way legal in the United States.

That’s where all the confusion started. Who has the power or legislative authority to do this? Does the 2018 Farm Bill repeal the Controlled Substances Act?

What does derivation and synthesis mean as a legal definition? Lawyers, businessmen, journalists, analysts, ordinary people, and Facebook karen have all offered their opinions, but so far no one has presented any of these theories to the court, and until they do, existing precedent will likely support the DEA’s decision. By the late spring of 2021, many states began banning Δ8-THC entirely rather than addressing the confusion.

Others have simply integrated it into the existing medicinal or recreational cannabis infrastructure by transferring it to cannabis companies licensed under the law to protect medicinal or adult use. The government’s inability or unwillingness to address this issue at the federal level has the same effect as the current regulation of cannabis, whether cannabis or marijuana.

Regulations vary significantly from state to state, creating an uneven playing field that leads to confusion, questionable practices, illegal markets, and potentially dangerous or, at best, mislabeled products.

In Florida, for example, you can buy products containing Δ8-THC at almost any roadside gas station. Since they are produced according to current legislation on cannabis cultivation, the only safety or quality control requirement is a Δ9-THC content of less than 0.3%.

By comparison : In Kentucky, Δ8-THC is completely banned in all forms.

So is this the beginning of the end for Δ8-THC? That’s unlikely. A number of factors could lead to the conclusion that Δ8-THC and its other isomers are likely to persist, but are likely to be regulated.

The discovery of THC seems to be fast approaching reality and is no longer the distant wishful thinking it has been for decades. The DEA is currently expanding access to marijuana for further investigation.

As more research is conducted on cannabinoids and more clinical data becomes available, it is likely that other isomers, such as Δ8-THC, will be used. As more and more states adopt regulations mandating safety testing for cannabis and CBD products, it is much more likely that Δ8-THC will be subject to similar regulations and will continue to be produced and sold despite being recognized as a psychoactive substance.

With this in mind, the current flood of Δ8-THC products on the market might just be a fad caused by the recent price drop in the CBD market. Thousands of CBD growers, processors and manufacturers are trying to deplete their CBD stocks and get a better price for Δ8-THC.Delta-8-THC (also known as THC-8) is a type of cannabidiol (CBD) with the same molecular formula, but with a higher proportion of the non-psychoactive cannabidiol. Compared to CBD-rich strains of cannabis, Delta-8-THC is typically less potent, yet still has a wide variety of therapeutic potential applications, including being a potential treatment for cancer and other diseases.. Read more about delta 8 gummies and let us know what you think.

Frequently Asked Questions

How do you synthesize Delta 8 THC?

Delta 8 THC is synthesized by first converting Delta 9 THC to Delta 8 THC.

What is the difference between Delta 8 THC and Delta 9 THC?

Delta 8 THC is the main psychoactive component of cannabis. Delta 9 THC is a non-psychoactive component of cannabis that has been shown to have some medicinal properties.

How do you convert CBD to d8 THC?

There is no direct conversion between CBD and THC.

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