A recent study found that cannabis is effective in reducing epileptic seizures, but there are a lot of interactions with other drugs we don’t yet know the full effects. Many patients may decide to take these medications while they’re switching over to cannabidiol (CBD) oil and edibles-what do you think?

There are many benefits to mixing cannabis and prescription drugs. The main benefit is that it can help reduce the amount of painkillers, antidepressants, or other medications that you need to take. It also has a positive effect on your mood and anxiety levels. Read more in detail here: cbd vs prescription drugs.

Is Mixing Cannabis And Prescription Drugs A Good Idea?



CBD or marijuana may assist with pain, but it may also make the other drug(s) you’re on more harmful.

Cannabis is well-known for its therapeutic properties, which include treating chronic pain, epilepsy, anxiety, and PTSD symptoms, among others.

However, recent study conducted by experts at Washington State University reveals that mixing cannabinoids, a group of compounds contained in the cannabis plant, with other prescription pharmaceuticals might result in hazardous drug-drug interactions (WSU).

Cannabinoids and their primary metabolites present in cannabis users’ blood were shown to interfere with two families of enzymes that assist digest a broad range of medications given for a variety of diseases, according to the researchers. As a consequence, with too much building up in the body, either the medications’ favorable benefits may diminish or their bad effects may rise, resulting in unanticipated side effects such as toxicity or unintentional overdose.

The researchers looked at how three of the most common cannabinoids – tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabinol – interacted (CBN).

While additional study is needed, the authors advise care when taking cannabis in conjunction with prescription medications.

“When patients use cannabis, physicians need to be aware of the danger of toxicity or lack of response,” said Philip Lazarus, senior author of the article and Boeing distinguished professor of pharmaceutical sciences. “It’s one thing if you’re young and healthy and sometimes smoke cannabis, but for elderly individuals on meds, using CBD or medical marijuana might interfere with their therapy.”

“It’s one thing if you’re young and healthy and smoke cannabis once in a while,” Lazarus said, “but consuming CBD or medical marijuana may have a detrimental influence on the treatment of elderly individuals who are on pharmaceuticals.”


The Results

Researchers employed human kidney cells that had been altered and validated their findings in human liver and kidney tissues that included enzymes.

Even while cannabinoids linger in the body for about 30 minutes before being swiftly broken down, the metabolites that arise from that process may persist in the system for up to 14 days, according to Shamema Nasrin, a graduate student in the WSU College of Pharmacy and Pharmaceutical Sciences.

Furthermore, she added that metabolites are detected “at greater quantities than cannabinoids,” and that they had been “missed in earlier investigations.”

Negative drug interactions may result in a reduction in the favorable benefits of the medication as well as an increase in the negative effects, culminating in an excessive build-up in the body that can cause unwanted side effects including toxicity or accidental overdose.

“Taking CBD or marijuana may relieve your pain, but it may also make the other medicine you’re taking more toxic, and that increase in toxicity may mean you won’t be able to continue taking that drug,” Nasrin said. “As a result, anti-cancer medications might have major consequences, and that’s just one of many treatments that could be damaged by the cannabinoid-enzyme interactions we’re observing.”

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The “methadone and cbd oil” is a question that is often asked. Mixing cannabis with prescription drugs can be a dangerous idea. There are many risks associated with mixing the two substances. The most common risk is the risk of overdose.

Frequently Asked Questions

What drugs should you not mix together?

A: There are many different types of drugs, and so it is difficult to answer this question. However, the following drugs should generally not be mixed together due to their side effects in large doses:

What drugs should not be taken with CBD?

A: Marijuana, heroin, LSD, cocaine and MDMA.

Can you eat edibles on medication?

A: There is no such thing as edibles on medication.

  • medical use of cannabinoids
  • nabiximols spray
  • does smoking affect medication
  • drug interaction tables
  • serotonin syndrome
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